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A flexible rank-based framework for detecting copy number aberrations from array data

Motivation: DNA copy number aberration—both inherited and sporadic—is a significant contributor to a variety of human diseases. Copy number characterization is therefore an area of intense research. Probe hybridization-based arrays are important tools used to measure copy number in a high-throughput...

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Detalles Bibliográficos
Main Authors: LaFramboise, Thomas, Winckler, Wendy, Thomas, Roman K.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732300/
https://ncbi.nlm.nih.gov/pubmed/19176555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp063
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