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Specific alignment of structured RNA: stochastic grammars and sequence annealing
Motivation: Whole-genome screens suggest that eukaryotic genomes are dense with non-coding RNAs (ncRNAs). We introduce a novel approach to RNA multiple alignment which couples a generative probabilistic model of sequence and structure with an efficient sequence annealing approach for exploring the s...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732270/ https://ncbi.nlm.nih.gov/pubmed/18796475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn495 |
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