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Activation and Repression Domains Within the Promoter of the Rat Cathepsin L Gene Orchestrate Sertoli Cell-Specific and Stage-Specific Gene Transcription in Transgenic Mice

In murine testes, only Sertoli cells express the cathepsin L (Ctsl) gene, and this expression is restricted to stages V–VIII of the cycle. Our previous transgenic analysis of Tg (−2065/+977) demonstrated that this expression is regulated by a ∼2-kb promoter. To begin to elucidate this regulation, we...

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Detalhes bibliográficos
Main Authors: Visone, Thomas, Charron, Martin, Wright, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731987/
https://ncbi.nlm.nih.gov/pubmed/19458314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.075952
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