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ANTIARRHYTHMIC DRUG-INDUCED INTERNALIZATION OF THE ATRIAL SPECIFIC K+ CHANNEL, Kv1.5

Conventional antiarrhythmic drugs target the ion permeability of channels, but increasing evidence suggests that functional ion channel density can also be modified pharmacologically. Kv1.5 mediates the ultrarapid potassium current (I(Kur)) that controls atrial action potential duration. Given the a...

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Detalhes bibliográficos
Main Authors: Schumacher, Sarah M., McEwen, Dyke P., Zhang, Lian, Arendt, Kristin L., Van Genderen, Kristin M., Martens, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731974/
https://ncbi.nlm.nih.gov/pubmed/19443837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.192773
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