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Using reads to annotate the genome: influence of length, background distribution, and sequence errors on prediction capacity
Ultra high-throughput sequencing is used to analyse the transcriptome or interactome at unprecedented depth on a genome-wide scale. These techniques yield short sequence reads that are then mapped on a genome sequence to predict putatively transcribed or protein-interacting regions. We argue that fa...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731892/ https://ncbi.nlm.nih.gov/pubmed/19531739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp492 |
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