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Differential remodeling of a T-cell transcriptome following CD8- versus CD3-induced signaling
CD8 engagement with class I major histocompatibility antigens greatly enhances T-cell activation, but it is not clear how this is achieved. We address the question of whether or not the antibody-mediated ligation of CD8 alone induces transcriptional remodeling in a T-cell clone, using serial analysi...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731849/ https://ncbi.nlm.nih.gov/pubmed/18475290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2008.56 |
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