N-Acetylcysteine as adjunctive treatment in severe malaria: A randomized double blinded placebo controlled clinical trial

OBJECTIVE: Markers of oxidative stress are reported to be increased in severe malaria. It has been suggested that the antioxidant N-acetylcysteine (NAC) may be beneficial in treatment. We studied the efficacy and safety of parenteral N-acetylcysteine as an adjunct to artesunate treatment of severe f...

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Autores principales: Charunwatthana, Prakaykaew, Faiz, M. Abul, Ruangveerayut, Ronnatrai, Maude, Richard, Rahman, M. Ridwanur, Roberts, L. Jackson, Moore, Kevin, Yunus, Emran Bin, Hoque, M. Gofranul, Hasan, Mahatab Uddin, Lee, Sue J., Pukrittayakamee, Sasithon, Newton, Paul N., White, Nicholas J., Day, Nicholas P.J., Dondorp, Arjen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731834/
https://ncbi.nlm.nih.gov/pubmed/19114891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181958dfd
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