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A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol

BACKGROUND: L-arabitol dehydrogenase (LAD) and xylitol dehydrogenase (XDH) are involved in the degradation of L-arabinose and D-xylose, which are among the most abundant monosaccharides on earth. Previous data demonstrated that LAD and XDH not only differ in the activity on their biological substrat...

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Detalhes bibliográficos
Main Authors: Rutten, Lucy, Ribot, Cecile, Trejo-Aguilar, Blanca, Wösten, Han AB, de Vries, Ronald P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731777/
https://ncbi.nlm.nih.gov/pubmed/19674460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-9-166
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