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The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?
Aging is the most important risk factor for common neurodegenerative disorders such as Parkinson’s and Alzheimer’s diseases. Aging in the central nervous system has been associated with elevated mutation load in mitochondrial DNA, defects in mitochondrial respiration and increased oxidative damage....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731695/ https://ncbi.nlm.nih.gov/pubmed/18403030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2008.02.008 |
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