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Restoration of immune response gene induction in trophoblast tumor cells associated with cellular senescence
Trophoblast cells and many cancer cells that harbor foreign antigens may evade immunity by epigenetic silencing of key immune response genes, including MHC class I and II and CD40. Chromatin active agents, such as histone deacetylase inhibitors (HDACi), induce immune response gene expression but oft...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731570/ https://ncbi.nlm.nih.gov/pubmed/19493573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jri.2009.02.009 |
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