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Sjögren’s Syndrome-Like Ocular Surface Disease in Thrombospondin-1 Deficient Mice
Thrombospondin-1 (TSP-1) is a major activator of latent transforming growth factor-β in vitro as well as in vivo. Mice deficient in TSP-1, despite appearing normal at birth, develop a chronic form of ocular surface disease that is marked by increased apoptosis and deterioration in the lacrimal gland...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Investigative Pathology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731132/ https://ncbi.nlm.nih.gov/pubmed/19700744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081058 |
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