Molecular genetics analysis of hereditary breast and ovarian cancer patients in India

BACKGROUND: Hereditary cancers account for 5–10% of cancers. In this study BRCA1, BRCA2 and CHEK2*(1100delC) were analyzed for mutations in 91 HBOC/HBC/HOC families and early onset breast and early onset ovarian cancer cases. METHODS: PCR-DHPLC was used for mutation screening followed by DNA sequenc...

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Main Authors: Soumittra, Nagasamy, Meenakumari, Balaiah, Parija, Tithi, Sridevi, Veluswami, Nancy, Karunakaran N, Swaminathan, Rajaraman, Rajalekshmy, Kamalalayam R, Majhi, Urmila, Rajkumar, Thangarajan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731042/
https://ncbi.nlm.nih.gov/pubmed/19656415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-7-13
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