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Bayesian comparison of Markov models of molecular dynamics with detailed balance constraint

Discrete-space Markov models are a convenient way of describing the kinetics of biomolecules. The most common strategies used to validate these models employ statistics from simulation data, such as the eigenvalue spectrum of the inferred rate matrix, which are often associated with large uncertaint...

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Detalhes bibliográficos
Main Authors: Bacallado, Sergio, Chodera, John D., Pande, Vijay
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730706/
https://ncbi.nlm.nih.gov/pubmed/19655927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3192309
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