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SUBSTITUTION OF METHIONINE 63 OR 83 IN S100A9 AND CYSTEINE 42 IN S100A8 ABROGATE THE ANTIFUNGAL ACTIVITIES OF S100A8/A9: POTENTIAL ROLE FOR OXIDATIVE REGULATION
S100A8 and S100A9 and their heterocomplex calprotectin (S100A8/A9) are abundant cytosolic constituents in human neutrophils previously shown to possess antifungal activity. This study was designed to investigate mechanisms involved in the modulation of the antifungal properties of S100A8/A9. S100A8,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730662/ https://ncbi.nlm.nih.gov/pubmed/19087201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-695X.2008.00498.x |
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