A molecular analysis of biclonal follicular lymphoma: further evidence for bone marrow origin and clonal selection

We report a follicular lymphoma (FL) case presenting the coexistence of two tumor cell subpopulations in lymph node (LN) and bone marrow (BM), which exhibited an inverse pattern of immunoglobulin light (IgL) chain gene rearrangement and expression: Igκ−λ+ in LN and Igκ+λ− in BM. These tumor clones s...

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Detalhes bibliográficos
Main Authors: Nakamura, Yuichi, Sato, Yasutaka, Yoshida, Katsuhiko, Kakegawa, Emi, Ito, Yoshihiro, Seyama, Atsushi, Kayano, Hidekazu, Bessho, Masami
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730550/
https://ncbi.nlm.nih.gov/pubmed/19220419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0609.2009.01233.x
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