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A molecular analysis of biclonal follicular lymphoma: further evidence for bone marrow origin and clonal selection

We report a follicular lymphoma (FL) case presenting the coexistence of two tumor cell subpopulations in lymph node (LN) and bone marrow (BM), which exhibited an inverse pattern of immunoglobulin light (IgL) chain gene rearrangement and expression: Igκ−λ+ in LN and Igκ+λ− in BM. These tumor clones s...

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Bibliografiske detaljer
Main Authors: Nakamura, Yuichi, Sato, Yasutaka, Yoshida, Katsuhiko, Kakegawa, Emi, Ito, Yoshihiro, Seyama, Atsushi, Kayano, Hidekazu, Bessho, Masami
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730550/
https://ncbi.nlm.nih.gov/pubmed/19220419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0609.2009.01233.x
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