Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb

The glycosaminoglycan hyaluronan (HA) is a structural component of extracellular matrices and also interacts with cell surface receptors to directly influence cell behavior. To explore functions of HA in limb skeletal development, we conditionally inactivated the gene for HA synthase 2, Has2, in lim...

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Detaylı Bibliyografya
Asıl Yazarlar: Matsumoto, Kazu, Li, Yingcui, Jakuba, Caroline, Sugiyama, Yoshinori, Sayo, Tetsuya, Okuno, Misako, Dealy, Caroline N., Toole, Bryan P., Takeda, Junji, Yamaguchi, Yu, Kosher, Robert A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2009
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730409/
https://ncbi.nlm.nih.gov/pubmed/19633173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.038505
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