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A breast cancer risk haplotype in the caspase-8 gene

Recent large-scale studies have been successful in identifying common, low penetrance variants associated with common cancers. One such variant in the caspase-8 (CASP8) gene, D302H (rs1045485), has been confirmed to be associated with breast cancer risk, although the functional impact of this polymo...

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Autori principali: Shephard, Neil Duncan, Abo, Ryan, Rigas, Sushila Harkisandas, Frank, Bernd, Lin, Wei-Yu, Brock, Ian Wallace, Shippen, Adam, Balasubramanian, Sabapathy Prakash, Reed, Malcolm Walter Ronald, Bartram, Claus Rainer, Meindl, Alfons, Schmutzler, Rita Katharina, Engel, Christoph, Burwinkel, Barbara, Cannon-Albright, Lisa Anne, Allen-Brady, Kristina, Camp, Nicola Jane, Cox, Angela
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730164/
https://ncbi.nlm.nih.gov/pubmed/19318553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4266
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