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Hydrogen Peroxide Stimulates the Ca(2+)-activated Big-Conductance K Channels (BK) Through cGMP Signaling Pathway in Cultured Human Endothelial Cells

We used the whole cell patch-clamp technique to examine the effect of hydrogen peroxide (H(2)O(2)) on the Ca(2+)-activated BK channels in human endothelial cells. We confirmed the previous finding that a 200 pS BK channel activity was detected when the cell membrane potential was clamped at 50 mV. A...

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Autors principals: Dong, De-Li, Yue, Peng, Yang, Bao-Feng, Wang, Wen-Hui
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730122/
https://ncbi.nlm.nih.gov/pubmed/18769038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000149789
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