Full Likelihood Analysis of Genetic Risk with Variable Age at Onset Disease—Combining Population-Based Registry Data and Demographic Information

BACKGROUND: In genetic studies of rare complex diseases it is common to ascertain familial data from population based registries through all incident cases diagnosed during a pre-defined enrollment period. Such an ascertainment procedure is typically taken into account in the statistical analysis of...

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Autores principales: Pitkäniemi, Janne, Varvio, Sirkka-Liisa, Corander, Jukka, Lehti, Nella, Partanen, Jukka, Tuomilehto-Wolf, Eva, Tuomilehto, Jaakko, Thomas, Andrew, Arjas, Elja
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730012/
https://ncbi.nlm.nih.gov/pubmed/19718441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006836
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