Parecoxib has non-significant long-term effects on bone healing in rats when administered for a short period after fracture

INTRODUCTION: Selective and non-selective cyclo-oxygenase (COX) inhibitors impair bone healing by inhibiting prostaglandin synthesis. The purpose of this study was to evaluate the long-term effect of parecoxib, a selective COX-2 inhibitor, on bone healing in rats, when it is applied in a pattern sim...

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Библиографические подробности
Главные авторы: Akritopoulos, Panagiotis, Papaioannidou, Paraskevi, Hatzokos, Ippokratis, Haritanti, Afroditi, Iosifidou, Eirini, Kotoula, Maria, Mirtsou-Fidani, Vassiliki
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2008
Предметы:
Basic Science
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729985/
https://ncbi.nlm.nih.gov/pubmed/18677494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00402-008-0707-6
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