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Rapid synthesis of the indole-indolone scaffold via [3+2] annulation of arynes by methyl indole-2-carboxylates

The reaction of methyl indole-2-carboxylates and arynes affords a very efficient, high yielding synthesis of a novel indole-indolone ring system, which tolerates considerable functionality, is broad in scope and proceeds under mild reaction conditions.

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Detalhes bibliográficos
Main Authors: Rogness, Donald C., Larock, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729915/
https://ncbi.nlm.nih.gov/pubmed/20161137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.04.047
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