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Oxaziridine-mediated enantioselective aminohydroxylation of styrenes catalyzed by copper(II) bis(oxazoline) complexes

We report an oxaziridine-mediated enantioselective aminohydroxylation of olefins catalyzed by a chiral copper(II) bis(oxazoline) complex. A variety of styrenic olefins undergo efficient aminohydroxylation with excellent regioselectivity and synthetically useful levels of enantioselectivty (up to 84%...

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Autori principali: Michaelis, David J., Williamson, Kevin S., Yoon, Tehshik P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729913/
https://ncbi.nlm.nih.gov/pubmed/20161136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2009.03.012
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