Pharmacogenetics of Solid Tumors: Directed Therapy in Breast, Lung, and Colorectal Cancer: A Paper from the 2008 William Beaumont Hospital Symposium on Molecular Pathology

Genetic variability in drug-metabolizing enzymes and signaling pathways affects chemotherapy-related toxicity and treatment outcome in cancer. In breast and colorectal cancer, polymorphisms in metabolic enzymes involved in tamoxifen and irinotecan therapies has led the U.S. Food and Drug Administrat...

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Detalhes bibliográficos
Main Authors: Snozek, Christine L.H., O'Kane, Dennis J., Algeciras-Schimnich, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729835/
https://ncbi.nlm.nih.gov/pubmed/19644023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2009.090003
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