α2-Adrenergic Receptors Attenuate Secretagogue-Induced Endocytosis and Promote Exocytosis of Intestinal NHE2 and NHE3

Adrenergic agonists, through activation of intestinal epithelial α2-adrenergic receptors (α2AR), inhibit electrolyte secretion and promote absorption. The mechanisms of action to promote basal Na(+) absorption and inhibit stimulated secretion are not understood completely. The effects of α2-agonists...

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Bibliografiske detaljer
Main Authors: Musch, Mark W., Arvans, Donna L., Paris, Hervé, Chang, Eugene B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Pharmacology and Experimental Therapeutics 2009
Fag:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729798/
https://ncbi.nlm.nih.gov/pubmed/19556451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.151910
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