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Is NF-κB a good target for cancer therapy? Hopes and pitfalls

NF-κB transcription factors play a key role in many physiological processes, such as innate and adaptive immune responses, cell proliferation, cell death, and inflammation. It has become clear that aberrant regulation of NF-κB and the signaling pathways that control its activity are involved in canc...

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Detalhes bibliográficos
Main Authors: Baud, Véronique, Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729321/
https://ncbi.nlm.nih.gov/pubmed/19116625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2781
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