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Is NF-κB a good target for cancer therapy? Hopes and pitfalls
NF-κB transcription factors play a key role in many physiological processes, such as innate and adaptive immune responses, cell proliferation, cell death, and inflammation. It has become clear that aberrant regulation of NF-κB and the signaling pathways that control its activity are involved in canc...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Pub. Group
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729321/ https://ncbi.nlm.nih.gov/pubmed/19116625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2781 |
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