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A Novel Method for Monitoring Monoclonal Antibody Production During Cell Culture

We describe a new format for surface-based fluoroimmunoassays that allows detection of biomolecule interactions without separation steps. The bioactive layer was immobilized on the surface of a glass substrate covered with silver islands that provide optical amplification of the distinctive fluoresc...

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Detalhes bibliográficos
Main Authors: Szmacinski, Henryk, Smith, Derek S., Hanson, Michael A., Kostov, Yordan, Lakowicz, Joseph R., Rao, Govind
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729163/
https://ncbi.nlm.nih.gov/pubmed/18438872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.21795
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