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Salt Intake Augments Hypotensive Effects of TRPV4: Functional Significance and Implication

To test the hypothesis that activation of the transient receptor potential vanilloid 4 (TRPV4) channel conveys a hypotensive effect that is enhanced during salt load, male Wistar rats fed a normal (NS, 0.5%) or high sodium (HS, 4%) diet for 3 weeks were given 4α-phorbol 12,13-didecanoate (4α – PDD),...

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Detalhes bibliográficos
Main Authors: Gao, Feng, Sui, Dexin, Garavito, R. Michael, Worden, R. Mark, Wang, Donna H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729143/
https://ncbi.nlm.nih.gov/pubmed/19075100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.117499
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