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Dominant Effect of Anti-angiogenesis in Combination Therapy Involving Cyclophosphamide and the VEGF Receptor Tyrosine Kinase Inhibitor Axitinib

PURPOSE: Anti-angiogenic drug treatment inhibits tumor growth by decreasing blood supply, which can also reduce the delivery of other therapeutic agents. Presently, we investigated the effect of the VEGF receptor tyrosine kinase inhibitor axitinib (AG-013736) on tumor vascular patency and chemothera...

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Bibliografiske detaljer
Main Authors: Ma, Jie, Waxman, David J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729124/
https://ncbi.nlm.nih.gov/pubmed/19147763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1174
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