Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events

Tumor hypoxia and the hypoxia-inducible factors (HIFs) play a central role in the development of cancer. To study the relationship between tumor growth, tumor hypoxia, the stabilization of HIF-1α, and HIF transcriptional activity, we have established an in vivo imaging tool that allows longitudinal...

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Hauptverfasser: Lehmann, Steffi, Stiehl, Daniel P., Honer, Michael, Dominietto, Marco, Keist, Ruth, Kotevic, Ivana, Wollenick, Kristin, Ametamey, Simon, Wenger, Roland H., Rudin, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729010/
https://ncbi.nlm.nih.gov/pubmed/19666490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901194106
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