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GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling

Congenital heart diseases (CHD) occur in nearly 1% of all live births and are the major cause of infant mortality and morbidity. Although an improved understanding of the genetic causes of CHD would provide insight into the underlying pathobiology, the genetic etiology of most CHD remains unknown. H...

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Bibliographische Detailangaben
Hauptverfasser: Kodo, Kazuki, Nishizawa, Tsutomu, Furutani, Michiko, Arai, Shoichi, Yamamura, Eiji, Joo, Kunitaka, Takahashi, Takao, Matsuoka, Rumiko, Yamagishi, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728998/
https://ncbi.nlm.nih.gov/pubmed/19666519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904744106
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