Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations type 2 diabetes patients enriched with nephropathy from an African American population

Previously we performed a genome scan for type 2 diabetes (T2DM) using 638 African-American (AA) affected sibling pairs from 247 families; non-parametric linkage analysis suggested evidence of linkage at 6q24-27 (LOD 2.26). To comprehensively evaluate this region we performed a 2-stage association s...

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Autores principales: Leak, Tennille S., Mychaleckyj, Josyf C., Smith, Shelly G., Keene, Keith L., Gordon, Candace J., Hicks, Pamela J., Freedman, Barry I., Bowden, Donald W., Sale, Michèle M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728933/
https://ncbi.nlm.nih.gov/pubmed/18560894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0523-7
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