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Contribution of Gene Amplification to Evolution of Increased Antibiotic Resistance in Salmonella typhimurium
The use of β-lactam antibiotics has led to the evolution and global spread of a variety of resistance mechanisms, including β-lactamases, a group of enzymes that degrade the β-lactam ring. The evolution of increased β-lactam resistance was studied by exposing independent lineages of Salmonella typhi...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Genetics Society of America
2009
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728858/ https://ncbi.nlm.nih.gov/pubmed/19474201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.103028 |
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