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Clinical, Neuropathological and Genotypic Variability in SNCA A53T Familial Parkinson's Disease

Individuals with familial Parkinson’s disease (PD) due to a monogenic defect can show considerable clinical and neuropathological variability. To identify factors underlying this variability, histopathological analysis was performed in two clinically different A53T α-synuclein heterozygotes from Fam...

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Detalhes bibliográficos
Main Authors: Markopoulou, K, Dickson, DW, McComb, RD, Wszolek, ZK, Katechalidou, L, Avery, L, Stansbury, MS, Chase, BA
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728685/
https://ncbi.nlm.nih.gov/pubmed/18389263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-008-0372-4
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