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Nucleic acid polymerases employ a general acid for nucleotidyl transfer

Nucleic acid polymerases catalyze the formation of DNA or RNA from nucleoside-triphosphate precursors. Amino acid residues in the active site of polymerases are thought to contribute only indirectly to catalysis by serving as ligands for the two divalent cations required for activity or substrate bi...

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Detalhes bibliográficos
Main Authors: Castro, Christian, Smidansky, Eric D., Arnold, Jamie J., Maksimchuk, Kenneth R., Moustafa, Ibrahim, Uchida, Akira, Götte, Matthias, Konigsberg, William, Cameron, Craig E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728625/
https://ncbi.nlm.nih.gov/pubmed/19151724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1540
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