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Nucleic acid polymerases employ a general acid for nucleotidyl transfer
Nucleic acid polymerases catalyze the formation of DNA or RNA from nucleoside-triphosphate precursors. Amino acid residues in the active site of polymerases are thought to contribute only indirectly to catalysis by serving as ligands for the two divalent cations required for activity or substrate bi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728625/ https://ncbi.nlm.nih.gov/pubmed/19151724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1540 |
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