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Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors

Heart disease is the leading cause of mortality and morbidity in the Western world. The heart has little regenerative capacity after damage, leading to much interest in understanding the factors required to produce new cardiac myocytes. Despite a robust understanding of the molecular networks regula...

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Autori principali: Takeuchi, Jun K., Bruneau, Benoit G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728356/
https://ncbi.nlm.nih.gov/pubmed/19396158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08039
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