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Immobilization of Alkaline Phosphatase on Microporous Nanofibrous Fibrin Scaffolds for Bone Tissue Engineering

Alkaline phosphatase (ALP) promotes bone formation by degrading inorganic pyrophosphate (PP(i)), an inhibitor of hydroxyapatite formation, and generating inorganic phosphate (P(i)), an inducer of hydroxyapatite formation. P(i) is a crucial molecule in differentiation and mineralization of osteoblast...

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Bibliografische gegevens
Hoofdauteurs: Osathanon, Thanaphum, Giachelli, Cecilia M, Somerman, Martha J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728207/
https://ncbi.nlm.nih.gov/pubmed/19501906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.05.022
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