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Immobilization of Alkaline Phosphatase on Microporous Nanofibrous Fibrin Scaffolds for Bone Tissue Engineering

Alkaline phosphatase (ALP) promotes bone formation by degrading inorganic pyrophosphate (PP(i)), an inhibitor of hydroxyapatite formation, and generating inorganic phosphate (P(i)), an inducer of hydroxyapatite formation. P(i) is a crucial molecule in differentiation and mineralization of osteoblast...

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Hlavní autoři: Osathanon, Thanaphum, Giachelli, Cecilia M, Somerman, Martha J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728207/
https://ncbi.nlm.nih.gov/pubmed/19501906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.05.022
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