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Rapsyn interacts with the muscle acetylcholine receptor via α-helical domains in the α, β, and ε subunit intracellular loops

At the developing vertebrate neuromuscular junction, the acetylcholine receptor becomes aggregated at high density in the postsynaptic muscle membrane. Receptor localization is regulated by the motoneuron-derived factor, agrin, and requires an intracellular, scaffolding protein called rapsyn. Howeve...

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Détails bibliographiques
Auteurs principaux: Lee, Young, Rudell, John, Ferns, Michael
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728176/
https://ncbi.nlm.nih.gov/pubmed/19482062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.05.057
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