Enhanced in vivo immunogenicity of SIV vaccine candidates with cationic liposome-DNA complexes in a rhesus macaque pilot study

This pilot study tested the immunogenicity of a novel cationic liposome-DNA complex (CLDC) immunomodulatory vaccine adjuvant. Combined with a specific antigen, CLDC enhanced anti-SIV immune responses induced by various SIV vaccine candidates. Rhesus macaques immunized in the presence of CLDC develop...

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Bibliographic Details
Main Authors: Fairman, Jeff, Moore, Joseph, Lemieux, Mathieu, Van Rompay, Koen, Geng, Yongzhi, Warner, John, Abel, Kristina
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728146/
https://ncbi.nlm.nih.gov/pubmed/18690014
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