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Diabetes-Relevant Regulation of cultured Blood Outgrowth Endothelial Cells
Many cell and tissue abnormalities in diabetes mellitus are mediated by auto- and paracrine TGFβ which is induced by high ambient glucose and glycated proteins. In most cell types TGFβ reduces cell proliferation and enhances apoptosis which are mediated through the TGFβ type I receptor, Alk5. In con...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728142/ https://ncbi.nlm.nih.gov/pubmed/19539633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2009.06.002 |
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