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Nonlinear electrophoretic response yields a unique parameter for separation of biomolecules

We demonstrate a unique parameter for biomolecule separation that results from the nonlinear response of long, charged polymers to electrophoretic fields and apply it to extraction and concentration of nucleic acids from samples that perform poorly under conventional methods. Our method is based on...

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Detalhes bibliográficos
Main Authors: Pel, Joel, Broemeling, David, Mai, Laura, Poon, Hau-Ling, Tropini, Giorgia, Warren, René L., Holt, Robert A., Marziali, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728113/
https://ncbi.nlm.nih.gov/pubmed/19706437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907402106
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