Nonlinear electrophoretic response yields a unique parameter for separation of biomolecules

We demonstrate a unique parameter for biomolecule separation that results from the nonlinear response of long, charged polymers to electrophoretic fields and apply it to extraction and concentration of nucleic acids from samples that perform poorly under conventional methods. Our method is based on...

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Bibliographic Details
Main Authors: Pel, Joel, Broemeling, David, Mai, Laura, Poon, Hau-Ling, Tropini, Giorgia, Warren, René L., Holt, Robert A., Marziali, Andre
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Physical Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728113/
https://ncbi.nlm.nih.gov/pubmed/19706437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907402106
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