Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression

Oxygen molecule modulates tumour response to radiotherapy. Higher radiation doses are required under hypoxic conditions to induce cell death. Hypoxia may inhibit the non-homologous end-joining DNA repair through down regulating Ku70/80 expression. Hypoxia induces drug resistance in clinical tumours,...

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Detalhes bibliográficos
Main Authors: Lara, Pedro C, Lloret, Marta, Clavo, Bernardino, Apolinario, Rosa M, Henríquez-Hernández, Luis Alberto, Bordón, Elisa, Fontes, Fausto, Rey, Agustín
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728103/
https://ncbi.nlm.nih.gov/pubmed/19660100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-4-29
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