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Genetic polymorphisms, their allele combinations and IFN-β treatment response in Irish multiple sclerosis patients

INTRODUCTION: IFN-β is widely used as first-line immunomodulatory treatment for multiple sclerosis. Response to treatment is variable (30–50% of patients are nonresponders) and requires a long treatment duration for accurate assessment to be possible. Information about genetic variations that predic...

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Bibliografiska uppgifter
Huvudupphovsmän: O’Doherty, Catherine, Favorov, Alexander, Heggarty, Shirley, Graham, Colin, Favorova, Olga, Ochs, Michael, Hawkins, Stanley, Hutchinson, Michael, O’Rourke, Killian, Vandenbroeck, Koen
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727921/
https://ncbi.nlm.nih.gov/pubmed/19604093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/PGS.09.41
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