Noninvasive Detection of EGFR T790M in Gefitinib or Erlotinib Resistant Non-Small Cell Lung Cancer

PURPOSE: Tumors from 50% of epidermal growth factor receptor (EGFR) mutant non - small cell lung cancer patients that develop resistance to gefitinib or erlotinib will contain a secondary EGFR T790M mutation. As most patients do not undergo repeated tumor biopsies we evaluated whether EGFR T790M cou...

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Bibliographic Details
Main Authors: Kuang, Yanan, Rogers, Andrew, Yeap, Beow Y., Wang, Lilin, Makrigiorgos, Mike, Vetrand, Kristi, Thiede, Sara, Distel, Robert J., A.Jaänne, Pasi
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727796/
https://ncbi.nlm.nih.gov/pubmed/19351754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2592
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