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Calpain Regulates Enterocyte Brush Border Actin Assembly and Pathogenic Escherichia coli-mediated Effacement
This study identifies calpain as being instrumental for brush border (BB) microvillus assembly during differentiation and effacement during bacterial pathogenesis. Calpain activity is decreased by 25–80% in Caco 2 lines stably overexpressing calpastatin, the physiological inhibitor of calpain, and t...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727654/ https://ncbi.nlm.nih.gov/pubmed/12764139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M304616200 |
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