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Calpain Regulates Enterocyte Brush Border Actin Assembly and Pathogenic Escherichia coli-mediated Effacement

This study identifies calpain as being instrumental for brush border (BB) microvillus assembly during differentiation and effacement during bacterial pathogenesis. Calpain activity is decreased by 25–80% in Caco 2 lines stably overexpressing calpastatin, the physiological inhibitor of calpain, and t...

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Detalhes bibliográficos
Main Authors: Potter, David A., Srirangam, Anjaiah, Fiacco, Kerry A., Brocks, Daniel, Hawes, John, Herndon, Carter, Maki, Masatoshi, Acheson, David, Herman, Ira M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727654/
https://ncbi.nlm.nih.gov/pubmed/12764139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M304616200
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