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Cancer cells suppress p53 in adjacent fibroblasts

The p53 tumor suppressor serves as a crucial barrier against cancer development. In tumor cells and their progenitors, p53 suppresses cancer in a cell-autonomous manner. However, p53 also possesses non-cell-autonomous activities. For example, p53 of stromal fibroblasts can modulate the spectrum of p...

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Detalhes bibliográficos
Main Authors: Bar, J, Feniger-Barish, R, Lukashchuk, N, Shaham, H, Moskovits, N, Goldfinger, N, Simansky, D, Perlman, M, Papa, M, Yosepovich, A, Rechavi, G, Rotter, V, Oren, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727601/
https://ncbi.nlm.nih.gov/pubmed/19060923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.445
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