Intramural Delivery of Rapamycin With α(v)β(3)-Targeted Paramagnetic Nanoparticles Inhibits Stenosis After Balloon Injury

BACKGROUND: Drug eluting stents prevent vascular restenosis but can delay endothelial healing. A rabbit femoral artery model of stenosis formation after vascular injury was used to study the effect of intramural delivery of α(v)β(3)-integrin–targeted rapamycin nanoparticles on vascular stenosis and...

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Autori principali: Cyrus, Tillmann, Zhang, Huiying, Allen, John S., Williams, Todd A., Hu, Grace, Caruthers, Shelton D., Wickline, Samuel A., Lanza, Gregory M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727458/
https://ncbi.nlm.nih.gov/pubmed/18292395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.156281
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