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Induced pluripotent stem cells and the stability of the differentiated state
For much of the last century, the differentiated state that characterizes the many cell types of an adult organism was thought to be stable and abrogated only in rare instances by transdifferentiation, metaplasia or cancer. This stability was thought to reside in the autoregulatory molecular circuit...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727431/ https://ncbi.nlm.nih.gov/pubmed/19543232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.142 |
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