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The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells
Glioblastoma multiforme (GBM) is a malignant astrocytoma of the central nervous system associated with a median survival time of 15 months, even with aggressive therapy. This rapid progression is due in part to the diffuse infiltration of single tumor cells into the brain parenchyma, which is though...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727355/ https://ncbi.nlm.nih.gov/pubmed/19435897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4859 |
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