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The CCR4-NOT Complex Physically and Functionally Interacts with TRAMP and the Nuclear Exosome

BACKGROUND: Ccr4-Not is a highly conserved multi-protein complex consisting in yeast of 9 subunits, including Not5 and the major yeast deadenylase Ccr4. It has been connected functionally in the nucleus to transcription by RNA polymerase II and in the cytoplasm to mRNA degradation. However, there ha...

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Autors principals: Azzouz, Nowel, Panasenko, Olesya O., Colau, Geoffroy, Collart, Martine A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727002/
https://ncbi.nlm.nih.gov/pubmed/19707589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006760
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