Safety, Reactogenicity and Immunogenicity of Francisella tularensis Live Vaccine Strain in Humans

We evaluated the safety, reactogenicity and immunogenicity of escalating doses of a new Francisella tularensis Live Vaccine Strain (LVS) lot by scarification (SCAR) or subcutaneously (SQ) in humans. Subjects (N=10/group) received one dose of LVS via SCAR at 10(5), 10(7) or 10(9) cfu/ml or SQ at 10(2...

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Detalhes bibliográficos
Main Authors: El Sahly, HM, Atmar, RL, Patel, SM, Wells, JM, Cate, T, Ho, M, Guo, K, Pasetti, MF, Lewis, DE, Sztein, MB, Keitel, WA
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726995/
https://ncbi.nlm.nih.gov/pubmed/19567246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.06.036
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